cutaneous hemangioma; Hemangiomas; vascular tumors of the skin
DefinitionThis section has been translated automatically.
The common classifications of cutaneous vascular tumors are based on morphological, clinical and histological criteria. In the case of vascular proliferates that appear clinically as a "tumour", it is often unclear whether they are:
- autochthonous neoplasias
- Neoplasia-like, reactive proliferations
- vascular malformations (vascular nevi)
ClassificationThis section has been translated automatically.
- Hamartomas and malformations:
- Hamartoma, eccrine, angiomatous
- Malformations, arteriovenous
- Lymphangiomas, superficial and deep:
- Capillary malformations:
- dilatations of pre-existing vessels:
- Naevus araneus
- Angioma, seniles of the lips (venous lake)
- Angiokeratomas (with enzymopathy):
- Angiokeratomas (without enzymopathy):
- Teleangiectasiasand teleangiectatic diseases.
- Cavernous malformations:
- Hemagiomas and reactive proliferations:
- Blue Rubber Bleb Nevus Syndrome
- infant hemangioma
- Hemangioma, tufted
- Hemangioma, microvenous
- Granuloma pyogenicum
- Angiomatosis, bacillary
- Bartonelless tickets
- Hemangioma, tardives
- Angioendotheliomatosis, reactive (benign)
- Hyperplasia, intravascular, papillary, endothelial
- Hemangioma, glomeruloid
- Angiolymphoid hyperplasia with eosinophilia
- Dermatofibroma, epitheloid cell
- Hemangioma, targetoid, hemosiderotic
- Hemangioma, spindle cell hemangioma
- Angioma serpiginosum.
- borderline and mildly malignant vascular tumors:
- Malignant vascular tumors:
- Angiomas with glomoid, pericyte or smooth muscle differentiation:
- Mesenchymal tumors with dominant vascular component:
HistologyThis section has been translated automatically.
Structural composition of vascular tumours:
- Vascular orientation (intra- or perivascular)
- Architecture (lobar or nodular/diffuse)
- Endothelial pattern (single layer or papillary multilayer)
- Vascular structure (organoid capillary vessels or bizarre vascular structures).
- Immunohistologically intravascular angiomas are defined as descendants of blood or lymph vessel endothelia, perivascular angiomas as descendants of smooth muscle cells or pericytes.
- Markers for endothelia are: CD31, ERG, FLI-1, factor VII-related antigen/v. Willebrand factor), CD34, Ulex europaeus.
- Markers for lymphatic endothelia are: D2-D40/Podoplanin, Prox1, LYVE1, VEGFR3 (vascular endothelial growth factor-3)
- In perivascular angiomas, reactivities for alpha smooth muscle actin, desmin, calponin, caldesmon are found.
LiteratureThis section has been translated automatically.
- Kutzner H (2003) Vascular tumors of the skin. In: Kerl H et al (Ed.) Histopathology of the skin. Springer Publishing House, Berlin Heidelberg New York, S. 759
- North PE et al (2003) Vascular neoplasms and neoplastic - like proliferations. In: Bologna J et al (ed.) Dermatology. Mosby, London New York Toronto, S. 1818
Incoming links (22)Aase syndrome; Angiokeratomas, acral pseudolymphomatous childhood; Angioma; Angioma; Bacillary angiomatosis; Blue nevus; Cowden syndrome; Diascopy; Dye laser; Focal nodular hyperplasia; ... Show all
Outgoing links (65)Acroangiodermatitis; Angioendotheliomatosis reactive (benign); Angiofibroma (overview); Angiohistiocytoma with giant cells; Angiokeratoma circumscriptum; Angiokeratomas (overview); Angiokeratome, solitary; Angioleiomyoma; Angiolipoma; Angiolymphoid hyperplasia with eosinophilia; ... Show all
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.