HistoryThis section has been translated automatically.
Howard and Helwig 1960
DefinitionThis section has been translated automatically.
Benign, solitary or multiple, slowly growing, often painful, vascular, soft or even solid nodes that can occur ubiquitously.
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LocalizationThis section has been translated automatically.
Extremities, trunk, even on the face.
Clinical featuresThis section has been translated automatically.
Sharply defined, shifting, relatively coarse, subcutaneous node. Frequently pressure-treated. Angiolipomas occur in > 50% of patients in the majority.
HistologyThis section has been translated automatically.
Circumscribed lobular tumor node made of mature adipocytes and provided with a delicate connective tissue capsule. A second tissue component is abundantly formed, often thrombosed vessels. A protruding or dominant vascular component is called a cell-rich angiolipoma (cellular angiolipoma). The cell-rich angiolipoma can occur together with the conventional lipoma. It shows reactivity for CD31 and CD34.
Differential diagnosisThis section has been translated automatically.
- Kaposi's Sarcoma
- Kaposi's angioendothelioma
TherapyThis section has been translated automatically.
Excision, in case of multiple occurrence, if necessary, drug therapy for pain.
LiteratureThis section has been translated automatically.
- Alonso S et al (2003) Metastasis of cutaneous malignant melanoma to angiolipoma: the tumor-to-tumor metastasis phenomenon. J Cutan catheter 30: 323-325
- Behrendt H et al (1992) Multiple Angiolipoma-analgesic therapy with doxepin. Dermatologist 43: 139-142
- De Poortere DA et al (2012) Nasal tip angiolipoma: the "Pinocchio" nasal deformity. Ear nose throat J 91:E1-4.
- Garib G et al (2015) Autosomal dominant familial angiolipomatosis. Cutis 95:E26-29.
- Gaskin CM et al (2004) Lipomas, lipoma variants, and well-differentiated liposarcomas (atypical lipomas): results of MRI evaluations of 126 consecutive fatty masses. AJR Am J Roentgenol 182: 733-739
- Kitagawa Y et al (2014) Subcutaneous angiolipoma: magnetic resonance imaging features with histological correlation. J Nippon Med Sch 81:313-319.
- Sheng Wet al (2013) Cellular angiolipoma: a clinicopathological and immunohistochemical study of 12 cases. At J Dermatopathol 35:220-225.
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