Department Internal medicine

PD-L1

PD-L1 Definition PD-L1 is synonymous with CD274 and plays a crucial role in the induction and maintenance of immune tolerance to self (Freeman GJ et al. (2000). PD-L1 aka CD274 is encoded by the PD-L1 gene located on chromosome 9p24.1.As a ligand for the inhibitory receptor PDCD1/PD-1, it modulat...