Pregnancy skin changes O99.7

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 13.10.2021

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Dermatoses of pregnancy; Pregnancy dermatoses; Pregnancy-specific dermatoses; Skin diseases during pregnancy

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Group of heterogeneous, physiological and pathological (so-called specific pregnancy dermatoses - usually accompanied by considerable itching) skin changes that occur during pregnancy and are largely reversible after pregnancy. Even pre-existing skin diseases can be influenced positively or negatively during pregnancy.

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A distinction is made between:

Pregnancy-related skin changes:

Dermatoses influenced by pregnancy:

Pregnancy-specific dermatoses:

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During pregnancy, complex endocrinological, immunological, metabolic and vascular changes lead on the one hand to the occurrence of pregnancy-specific physiological (skin) changes, which are largely reversible after pregnancy. On the other hand, pregnancy-specific pathological (skin) changes can manifest themselves. Furthermore, diseases can be defined which can be changed positively or negatively by a pregnancy (see classification).

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S.u. and the respective clinical picture. Basically, in case of considerable itching:

  • Cooling gels, moist compresses, cool shower.
  • Tannin 3-5% in Lotio alba (apply very thinly)
  • Urea (3-5%), menthol (1-2%) or polidocanol (2-5%) in cream or lotion base (e.g. Unguentum emulsificans aquosum or
  • "Underdosed" non-halogenated topical glucocorticoids (e.g. 0.5% hydrocortisone acetate)
  • Systemic glucocorticoids for severe itching problems. Prednisolone usually only short-term therapy (<4 weeks). In the 1st trimenon, do not exceed the dose of 10-15mg/day for longer use.
  • Systemic antihistamines(Dimetinden, Clemastine)

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The influence of pregnancy on the prognosis of women with melanoma was clearly negated in 10 case-control studies. In several large studies, no difference could be demonstrated with regard to overall survival or disease-free survival with adequate therapy. There is no need to refuse pregnancy in women with a previous melanoma disease. Women in a later stage of melanoma disease should be informed about the increased risk that their child may grow up motherless.

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  1. Ambros-Rudolph CM (2006) Dermatoses of pregnancy. J Dtsch Dermatol Ges 4: 748-759
  2. Ambros-Rudolph CM (2010) Specific pregnancy dermatoses. Dermatologist 61: 1014-1020
  3. Böer B et al.(2014) Skin diseases and allergies during pregnancy. Act Dermatol 40: 457-467


Please ask your physician for a reliable diagnosis. This website is only meant as a reference.


Last updated on: 13.10.2021