Autoimmune progesterone dermatitis in pregnancy O99.7

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Autoimmune progesterone dermatitis of pregnancy

History
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Géber, 1921; Shelley et al., 1964; Biermann, 1973

Definition
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Very rare autoimmune disease with sensitization to progesterone during pregnancy (see below pregnancy, skin changes) or under oral anti-conception with variable clinical manifestations. Beginning in early pregnancy. In addition to various skin eruptions during pregnancy, recurrent, premenstrual, glucocorticoid-resistant, volatile exanthema may occur. Recurrences can occur in subsequent pregnancies.

Diagnosis
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Intracutaneous and epicutaneous tests for progesterone.

Differential diagnosis
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Other pregnancy dermatoses.

Therapy
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Targeted measures not known. Symptomatic therapy in cooperation with the gynaecologist.

Progression/forecast
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Spontaneous abortion, recurrences in subsequent pregnancies.

Literature
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  1. Biermann SM (1973) Autoimmune progesterone dermatitis of prednancy. Arch Dermatol 107: 896-901
  2. Géber H (1921) Some data on the pathology of urticaria menstruationalis. Dermatol Period 32: 143-50
  3. Katayama I et al (1985) Autoimmune progesterone dermatitis with persistent amenorrhea. Br J Dermatol 112: 487-491
  4. Lens R et al (1978) Autoimmune progesterone dermatosis. Dermatol Mschr 164: 656-661
  5. Oskay T et al (2002) Autoimmune progesterone dermatitis. Eur J Dermatol 12: 589-591
  6. Shelley WB, Preucel RW, Spoont SS (1964) Autoimmune progesterone dermatitis. JAMA 190: 147-150
  7. Snyder JL et al (2003) Autoimmune progesterone dermatitis and its manifestation as anaphylaxis: a case report and literature review. Ann Allergy Asthma Immunol 90: 469-477

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020