debonding of the nail; Nail Detachment; nail removal; Onycholysis
DefinitionThis section has been translated automatically.
ClassificationThis section has been translated automatically.
- External causes (onycholysis as an isolated phenomenon).
- Toxic degenerative due to constant water contact (see below Onycholysis, partial)
- Traumatic (constant leverage), this concerns especially the onycholysis of the toenails - here tight footwear. Also due to incorrect nail modeling (artificial nails too long, constant leverage effects on the natural nail).
- UV -rays photoonycholysis - (without influence of sensitizing drugs)
- Primary skin diseases (with nail involvement)
- Psoriatic diseases of hands or feet (psoriatic onycholysis)
- Psoriatic arthritis (also without psoriatic skin manifestations)
- Erythema multiforme
- Alopecia areata (especially to be observed in alopecia areata totalis)
- Dysplasia, ectodermal
- Atopic dermatitis especially with acral involvement
- Pachyonychia congenita
- Parakeratosis Hjorth-Sabouraud
- POPP syndrome
Hereditary distal onycholysis with scleronychia
- Metabolic/systemic diseases
- Hyperthyroidism/hypothyroidism possibly in combination with autoimmune thyroiditis (see thyroid disorders skin lesions below); onycholysis may be an early indicator (Malan M et al. 2019)
- Yellow-nail syndrome
- chronic graft-versus-host disease
- M. Crohn's disease (painful onycholysis described)
- Chronic terminal renal failure especially in long-term dialysis (see below renal diseases, skin changes), protoporphyria erythropoetica (photoonycholysis)
- benign and malignant subungual tumors with secondary onycholysis
- subungual exostoses
- subungual malignant melanoma
- subungual squamous cell carcinoma
LiteratureThis section has been translated automatically.
- Bentabet Dorbani I et al (2012) Griseofulvin-induced photo-onycholysis. Press Med 41:879-881
- Cabanillas M et al (2011) Ischemic onycholysis of the hands. Cutis 87:287-288
- Cantatore-Francis JL et al (2010) Hepatoerythropoietic porphyria misdiagnosed as child abuse: cutaneous, arthritic, and hematologic manifestations in siblings with a novel UROD mutation. Arch Dermatol 146:529-533
- Edwards F et al (2009) Nail psoriasis: clinical presentation and best practice recommendations. Drugs 69:2351-1361
- Kolde G (2014) Onychomades after hand-foot-mouth disease. Nude Dermatol 40: 137-138
- Lau CP et al (2011) Docetaxel-induced nail toxicity: a case of severe onycholysis and topic review. Chin Med J 124:2559-2560
- Love TJ et al (2012) Psoriatic arthritis and onycholysis -- results from the cross-sectional Reykjavik psoriatic arthritis study. J Rheumatol 39:1441-1444
- Malan M et al (2019) Onycholysis an early indicator of thyroid disease.
Pan Afr Med J 32:31.
- Onelmis H et al (2012) Cutaneous changes in patients with chronic renal failure on hemodialysis. Cutan Ocul Toxicol 31:286-291
- Shemer A et al (2013) Common nail disorders. Clin Dermatol 31:578-586
- Vélez NF et al (2014) Simple onycholysis: a diagnosis of exclusion. J Am Acad Dermatol 70:793-794
- Zaias N et al (2014) Finger and toenail onycholysis. J Eur Acad Dermatol Venereol. doi: 10.1111/jdv.12862.
Incoming links (19)Acute paronychia; Alopecia areata totalis; Anonychie acquired; Candida paronychia; Doxorubicin; Dyskeratosis follicularis; Ectodermal dysplasia ; Isolated anonychy-onycholysis; Nail lichen planus ; Onycholysis drug-induced or light-induced; ... Show all
Outgoing links (30)Alopecia areata totalis; Anonychia (overview); Atopic hand dermatitis; Crohn disease, skin alterations; Dermatophytes; Ectodermal dysplasia ; Erythema multiforme; Graft-versus-host disease chronic; Griseofulvin; Hand-foot syndrome; ... Show all
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.