Mould diseases B48.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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  • The pathogenic importance of moulds extends mainly to the areas of secondary and opportunistic infections and to allergological phenomena (type I sensitisation, see mould allergy below), which primarily occur on the mucous membranes of the respiratory tract.
  • Mould fungus infections on the skin often occur as a beneficiary of an already existing dermatophyte infection, e.g. with Tinea unguium. Here they lead to different colour changes: Scopulariopsis brevicaulis leads to a brown colour, Alternaria and Cladosporium infections to a dark to black shade. However, they can also be the primary cause of skin infections (e.g. nail mycosis or granulomatous local infections, the diagnosis of which is random).
  • Among the species relevant for mould sensitization are Aspergillus, Penicillium and Cladosporium.
  • Furthermore, moulds play an important role as pathogens of opportunistic infections in patients with immunosuppression and/or under long-term antibiotic therapy.
  • The most frequent systemic mould mycoses are caused by species of the genus Aspergillus as well as by species from the group of zygomycetes ( Mucor, Rhizopus, Absidia), s.a. Cephalosporiosis, Verticilliosis, Hemisporosis, Peyronellaeosis, Myzetome, Chromomycosis, Black Piedra, Cutaneous Alternariosis. Less frequent are infections caused by Fusarium species (see Fusarium solani below).

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S.u. and the respective clinical picture.

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  1. Brasch J (2012) News on diagnostics and therapy of mycoses. Dermatologist 63: 390-395
  2. Brasch J et al (2008) Cutaneous phaeohyphomycosis caused by Alternaria infectoria. Case report and short review. Acta Dermatovenereol 88: 160-161


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Last updated on: 29.10.2020