Pseudomonas infections B96.5

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Pseudomonas; Pseudomonas aeruginosa; Pseudomonas skin infection; Pseudomonas skin infections

Definition
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Infections by representatives of the genus Pseudomonas.

Pseudomonas is a genus of rod-shaped, aerobic, gram-negative, motile bacteria, the size of which varies between 0,5-1,0 × 1,5-5,0 um. Pseudomonads occur ubiquitously (so-called "puddle germ") in soil, water on plants and animals. Species such as Pseudomonas aeruginosa, Pseudomonas pseudomallei, Pseudomonas mallei can be pathogenic for humans, especially in immunocompromised individuals. It is important that the pseudomonads are resistant to antibiotics.

Pseudomonads are able to form biofilms (mucus) at higher cell density, which protect them against macrophages and antibiotics.

Wound infections caused by P. aeruginosa are characterised by their blue-greenish colour and their unpleasantly sweet odour (e.g. in gram-negative foot infections).

Classification
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The following diseases are caused or co-caused by Pseudomonas species:

Therapy
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Acylaminopenicillins such as azlocillin and piperacillin, third generation cephalosporins (especially ceftazidim and cefepim; ceftriaxone, however, is not effective), newer fluoroquinolones and carbapenems are suitable for therapy.

Literature
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  1. Wu DC et al (2011) Pseudomonas skin infection: clinical features, epidemiology, and management. At J Clin Dermatol 12:157-69.https://www.ncbi.nlm.nih.gov/pubmed/21469761

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020