Panniculitis infectious M79.3
Synonym(s)
infectious panniculitis; panniculitis infection
Definition
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Pathogen-induced inflammatory reaction of the subcutaneous fatty tissue. Frequently occurring in immunocompromised patients.
Pathogen
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- Bacteria: Staphylococci, Streptococci, Pseudomonas, Klebsiellae, Yersinia, Tropheryma whippelii, Nokardia, Fusarium, Borrelia, Mycobacteria.
- Fungi: Candia species, moulds, histoplasms, cryptococci, sporotrichia.
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Etiopathogenesis
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Infection by direct inoculation of contaminated material or by septic metastases.
Clinic
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Mostly painful, deep lying, inflammatory nodes with red skin overlying them. Tendency to abscess and fistula formation.
Histology
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Septolobular neutrophilic panniculitis in the acute stage. Later very different infiltrates depending on the pathogen spectrum.
Diagnosis
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Pathogen detection by smear, culture, PCR.
Differential diagnosis
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Panniculitides of other genesis.
Therapy
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Depending on the pathogen spectrum.
Literature
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- Morrison LK et al (2010) Infection and panniculitis.dermatol Ther 23: 328-340
- Patterson JW et al (1989) Infection-induced panniculitis. J CutanPathol 16:183-193
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Pseudomonas infections;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer