Onycholysis totalis L60.13

Onycholysis with complete detachment of the entire nail plate from the matrix region (Hardin J et al. 2015), whereby the detached nail is usually replaced by a new one. The abrupt dystrophic disturbance of the nail can also be understood as the maximum form of Beau-Reile's transverse furrows.

Multifactorial genesis:

• Infection-allergic, e.g. after scarlet fever, Coxsackie virus infections, varicella, purulent paronychia and other infectious diseases
• after traumatisation
• Drug-induced (chemotherapeutics, antiepileptics, antibiotics, lithium, gold preparations)
• in association with other diseases such as Alopecia areata, Lichen planus, erythroderma, Lyell syndrome
• Systemic diseases (mycosis fungoides, Stevens-Johnson syndrome, TEN, Kawasaki syndrome; peritoneal dialysis)

1. Hamm H et al (2018) Diseases of the nails. In: Braun-Falco`s Dermatology, Venerology Allergology G. Plewig et al. (Hrsg) Springer Verlag S 1388-1389
2. Hardin J et al (2015) Onychomadesis: literature review. Br J Dermatol 172:592-596.
3. Salgado F et al (2017) Shedding light on onychomadesis.Cutis 99:33-36.