Deposit dermatoses (overview) L98.9

Heterogeneous group of etiologically different diseases characterized by the deposition of endogenous or also exogenous substances in the dermis and/or subcutis.

Classification of endogenous and exogenous deposition dermatoses:

Deposit dermatoses are easily recognizable from a clinical perspective. Unnatural discolorations of the skin indicate deposits of colored substances. Palpable, unaccustomed increases in consistency indicate accumulations of foreign substances (calcifications, ossifications, amyloid and others). In everyday clinical practice, such a finding provides histological clarification.

In endogenous deposition dermatoses, the body's own degradation products or incorrectly formed substances (e.g. amyloid) are deposited. It is often unclear whether increased formation or reduced breakdown is responsible for the deposition.

In exogenous deposition dermatoses, substances introduced from outside remain in the skin.

1. Müller CSL et al (2016) Cutaneous deposition dermatoses - the skin as a waste bin? What should the clinician know? Act Dermatol 42: 79-89