Synonym(s)
HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Sexually transmitted infectious disease (STI) caused by Haemophilus ducreyi, which is rare in industrialised countries and no longer subject to compulsory notification.
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PathogenThis section has been translated automatically.
EtiopathogenesisThis section has been translated automatically.
Transmission of H. ducreyi by sexual intercourse or smear infection after contact with skin lesions in already infected persons.
LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
Incubation period: 2-5 days. Rapidly disintegrating papules, formation of soft, greasy coated, painful ulcers with undermined margins. Some ulcers heal spontaneously after several weeks, even untreated. In case of progression, development of unilateral, highly painful regional lymphadenitis. There is a tendency to purulent melting of the lymph nodes. Fistulas often follow.
Further inoculation of the ulcers on adjacent skin areas (autoinoculation) is possible.
Special forms:
DiagnosisThis section has been translated automatically.
Notice! Repeated control of syphilisserology!
Differential diagnosisThis section has been translated automatically.
External therapyThis section has been translated automatically.
Notice! Surgical lymph node incision is usually not necessary!
Internal therapyThis section has been translated automatically.
Systemic Antibiosis, see Table 1 / p.a. p. 17 of the current guidelines of the STI Society
Remember! Control and if necessary treatment of the sexual partner is necessary, even if he or she does not show any symptoms!
Progression/forecastThis section has been translated automatically.
TablesThis section has been translated automatically.
Antibiotic therapy of the ulcer molle
Active substance |
Example preparations |
Dosage |
|
Medium 1st choice |
Azithromycin |
Zithromax |
Single dose: 1000 mg p.o. |
Erythromycin |
Erythrocin Filmtbl., Eryhexal Kps., Erythromycin Wolff Filmtbl. |
4 times 500 mg/day p.o. over 7 days |
|
| |||
Alternatively |
Ceftriaxone |
Rocephin |
0,25 g i.m. as single dose |
| |||
With simultaneous HIV infection |
Ciprofloxacin |
Ciprobay Filmtbl. |
2 times 500 mg/day p.o. over 3-5 days |
Amoxicillin/Clavulanic acid |
Augmentan Filmtbl. |
500/125 mg/day p.o. over 3-5 days |
|
LiteratureThis section has been translated automatically.
- Dt. Gesellschaft zur Bekämpfung der Geschlechtskrankheiten (1992) Guidelines for the diagnosis and treatment of sexually transmitted diseases.
- Ducrey A (1889) Il virus dell'ulcera venerea. Gazz Internaz Med Chir (Naples) 11: 44
- Ducrey A (1889) Experimental studies of the soft chancre and the bubons Monthly practical Dermatol 9: 387-405
- Kaur C et al (2002) Erythema nodosum induced by chancroid. Sex Transm Infect 78: 388-389
- Korting HC et al (1989) Diagnosis and therapy of the ulcer molle today. dermatologist 40: 418-422
- Krefting R (1892) About the microbe specific for ulcus molle. Arch Dermatol Syphil (Berlin) 2nd supplement: 41-62
- Kyriakis KP et al (2003) Incidence determinants of gonorrhea, chlamydial genital infection, syphilis and chancroid in attendees at a sexually transmitted disease clinic in Athens, Greece. Int J Dermatol 42: 876-881
- Lewis DA (2003) Chancroid: clinical manifestations, diagnosis, and management. Sex Transm Infect 79: 68-71
- Steen R (2001) Eradicating chancroid. Bull World Health Organ 79: 818-826
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Incoming links (24)
Acutal ulcer; Anal fissure; Chancre; Chancrelle; Chancre mou; Chancroéde; Chancroid; Ducrey-unna disease; Enoxacin; Erythromycin; ... Show allOutgoing links (16)
Donovanosis; Fusidic acid; Papel; Polihexanide; Potassium permanganate; Povidone-iodine; Syphilisserology; Ulcer durum; Ulcus mixtum; Ulcus molle elevatum; ... Show allDisclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer