Synonym(s)
HistoryThis section has been translated automatically.
DefinitionThis section has been translated automatically.
Very rare dermatosis of unexplained genesis, controversial in its autonomy, characterized by the coexistence of eczematous, lichenoid and urticarial foci with distinct itching.
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ManifestationThis section has been translated automatically.
Mainly middle-aged men. Children or women are affected less frequently.
LocalizationThis section has been translated automatically.
Clinical featuresThis section has been translated automatically.
Unbearably severe pruritus. Rapid succession or simultaneous appearance of exudative, reddened, infiltrated, nummular plaques, reminiscent of nummular dermatitis, lichenified papules or small urticarial papules. The skin lesions are extremely resistant to treatment.
LaboratoryThis section has been translated automatically.
HistologyThis section has been translated automatically.
Perivascular infiltrates from lymphocytes, granulocytes, eosinophils, plasma cells. Swelling of the vascular endothelia (unspecific image).
Differential diagnosisThis section has been translated automatically.
Nummular dermatitis; Scattering contact dermatitis; dermatitis herpetiformis; Lichen planus; Mycosis fungoides; Drug exanthema; Seborrheic dermatitis; Pityriasis rosea;
External therapyThis section has been translated automatically.
Internal therapyThis section has been translated automatically.
Therapy of the 1st choice are glucocorticoids, perorally, in medium dosage, initial 60-80 mg/day prednisolone equivalent, slow release to low maintenance dose over several weeks. After discontinuation the skin symptoms flare up again. The glucocorticoids can only be completely eliminated after months or years.
Cases with healing under exclusive azathioprine therapy (e.g. Imurek) are described. An attempt at therapy with antihistamines such as desloratadine (e.g. Aerius) 1-2 tbl/day or levocetirizine (e.g. Xusal) 1-2 tbl/day is possible.
Progression/forecastThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Jansen T et al (1992) Sulzberger-Garbe exudative discoid and lichenoid chronic dermatosis ("Oid-Oid disease")--reality or fiction? dermatologist 43: 426-
- Savill T (1891) On an epidemic skin disease. Br Med J (London) 2: 1197-1202
- Stevens DM et al (1984) On the concept of distinctive exudative discoid and lichenoid chronic dermatosis (Sulzberger's scar). At J Dermatopathol 6: 387-395
- Sulzberger MB, Garbe W (1937) Nine cases of a distinctive exudative discoid and lichenoid chronic dermatosis. Arch Dermatol (Chicago) 36: 247-278
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Incoming links (8)
Betamethasone valerate emulsion hydrophilic 0,025/0,05 or 0,1 % (nrf 11.47.); Dermatosis, exudative discoid lichenoid; Dermatosis, exudative discoid lichenoid, chronic; Eosinophilia and skin; Exudative discoid lichenoid dermatitis; Oid-oid-disease; Sulzberger-garbe syndrome; Triamcinolone acetonide cream hydrophilic 0,025/0,05/0,1% (nrf 11.38.);Outgoing links (19)
Adverse drug reactions of the skin; Antihistamines, systemic; Azathioprine; Betamethasone valerate emulsion hydrophilic 0,025/0,05 or 0,1 % (nrf 11.47.); Contact dermatitis (overview); Dermatitis herpetiformis; Desloratadine; Eczema (overview); Glucocorticosteroids systemic; Glucorticosteroids topical; ... Show allDisclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer
