Dermatitis exudative discoid lichenoid L98.8

Very rare dermatosis of unexplained genesis, controversial in its autonomy, characterized by the coexistence of eczematous, lichenoid and urticarial foci with distinct itching.

Mostly middle-aged men.

Unbearably severe pruritus. Rapid succession or simultaneous appearance of exudative, reddened, infiltrated, nummular plaques, reminiscent of nummular dermatitis, lichenified papules or small urticarial papules. The skin lesions are extremely resistant to treatment.

Perivascular infiltrates from lymphocytes, granulocytes, eosinophils, plasma cells. Swelling of the vascular endothelia (unspecific image).

Nummular dermatitis; Scattering contact dermatitis; dermatitis herpetiformis; Lichen planus; Mycosis fungoides; Drug exanthema; Seborrheic dermatitis; Pityriasis rosea;

Therapy of the 1st choice are glucocorticoids, perorally, in medium dosage, initial 60-80 mg/day prednisolone equivalent, slow release to low maintenance dose over several weeks. After discontinuation the skin symptoms flare up again. The glucocorticoids can only be completely eliminated after months or years.

Cases with healing under exclusive azathioprine therapy (e.g. Imurek) are described. An attempt at therapy with antihistamines such as desloratadine (e.g. Aerius) 1-2 tbl/day or levocetirizine (e.g. Xusal) 1-2 tbl/day is possible.

1. Jansen T et al (1992) Sulzberger-Garbe exudative discoid and lichenoid chronic dermatosis ("Oid-Oid disease")--reality or fiction? dermatologist 43: 426-
2. Savill T (1891) On an epidemic skin disease. Br Med J (London) 2: 1197-1202
3. Stevens DM et al (1984) On the concept of distinctive exudative discoid and lichenoid chronic dermatosis (Sulzberger's scar). At J Dermatopathol 6: 387-395
4. Sulzberger MB, Garbe W (1937) Nine cases of a distinctive exudative discoid and lichenoid chronic dermatosis. Arch Dermatol (Chicago) 36: 247-278