Postthrombotic syndrome I87.0-

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Decompensatory symptoms after expired phlebothrombosis with formation of secondary varicose veins, increased peripheral venous pressure, stasis oedema, permanent fluid infiltration into the tissue with disturbances in the exchange of substances as well as inflammatory, degenerative and productive ( dermatoliposclerosis) tissue reactions. The consequences are restrictions in the quality of life due to venous claudication and ulcers.

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The incidence of PTS is reported to be between 29% and 82%, depending on the severity and location of the thrombosis (thromboses of the inferior vena cava or the iliac veins have a high risk of developing PTS).

Clinical features
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Different degrees of severity:

still within the framework of developing chronic venous insufficiency:

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Symptomatic therapy according to the clinic, see below Venous insufficiency, chronic.

A few years ago, patients with PTS were considered "not to touch". In the meantime, after Doppler sonographic diagnosis, the aim is to interrupt insufficient perforating veins. A bypass circulation should not be disturbed. Furthermore, suitable operative venous valve reconstructions can improve the functional condition of the venous system.

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  1. Czihal M et al (2012) Impact of the postthrombotic syndrome on quality of life after primary upper extremity deep venous thrombosis. Vasa 41:200 204.
  2. Grommes J et al. (2012) New endovascular treatment options of deep vein thrombosis. German Med Weekly 137:1524-1529
  3. Vazquez SR et al (2012) Advances in the diagnosis and management of postthrombotic syndrome. Best Pract Res Clin Haematol 25:391-402


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Last updated on: 29.10.2020