Meliloti herba

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 14.08.2023

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Synonym(s)

Sweet clover

Definition
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Medicinally used above-ground plant parts of sweet clover and sweet clover (Melilotus officinalis) collected at flowering time, but also the herb of sweet clover (Melilotus altissima).

HMPC Monograph: Traditional-use: Internally and externally for mild venous circulatory disorders, leg heaviness, externally mild skin inflammation.
ESCOP Monograph: Internally: Chronic venous insufficiency for leg pain and heaviness, night cramps, itching and swelling.
Commission-E-Monograph: Internal: Chronic venous insufficiency with pain and heaviness in the legs, night cramps in the calves, itching and swelling; supportive in thrombophlebitis, post-thrombotic syndrome, hemorrhoids, lymphatic congestion; external: contusions, sprains, superficial bruises.

Empirical medicine: joint inflammation, boils and carbuncles (as a herbal pillow).

Ingredients
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The medically used herb of Melilotus officinalis (Herba Meliloti) contains coumarin derivatives, especially melilotonide, from which the volatile coumarin is produced, which causes the typical coumarin smell of hay. Also melitonin (a dihydrocoumarin), flavonoids with the aglycans quercetin and kaemperol; also saponins, phenolic carboxylic acids, essential oils.

Effects
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Anti-oedematous in inflammatory oedema and stasis oedema, antiexudative, accelerates wound healing.

Field of application/use
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Preparation: Crushed drug as tea infusion for internal and external use.
Preparation: 1-2Tl drug to one cup of boiling water, strain after 10 min, dosage 2-3 cups per day.

Internal: symptoms of CVI, nocturnal calf cramps, itching, swellingExternal
: bruises, haematomas, superficial thrombophlebitis, postthrombotic syndrome, haemorrhoids, lymphatic congestion, also with boils (no evidence)

Pregnancy/nursing period
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Systemic applications are not recommended as no data is available.

Undesirable effects
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Internal use: Rarely headache, gastrointestinal complaints,

external use: allergic reactions

Contraindication
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Hypersensitivity to the active substances; children and adolescents under 18 years of age

Interactions
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Systemic application increases the effect of anticoagulants, especially coumarin-type anticoagulants.

Trade names
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Venolat® capsules and ointment, Veno-Dolan® drops and capsules, combination products; Phlebodril® cream

Note(s)
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No systemic use in persons < 18 years. The above mentioned effects are sufficiently proven in animal experiments. There are no reliable clinical studies.

Literature
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  1. https://arzneipflanzenlexikon.info/steinklee.php
  2. https://www.ema.europa.eu/en/documents/herbal-monograph/final-european-union-herbal-monograph-melilotus-officinalis-l-lam-herba_en.pdf
  3. Wenigmann M.(2017) Phytotherapy medicinal drugs phytopharmaceuticals application. Urban & Fischer: 5.108 Sweet clover (Meliloti herba) p 198-199.