Aescin

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 29.10.2020

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Synonym(s)

Horse Chestnut Extract

Definition
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Mixture of esterified triterpene saponins (see below triterpene) from the seeds of the horse chestnut.

Effects
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Low spasmolytic, antiphlogistic, anti-edematous, increase of capillary permeability (slows down the flow of water into the extracapillary space).

Notice! Percutaneous absorption is questionable!

Field of application/use
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Chronic venous insufficiency, post-thrombotic syndrome, leg ulcers, post-traumatic and postoperative soft tissue swelling, hemorrhoids.

Dosage
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  • Systemic: Inital 3 times 20-40 mg/day, then 2-3 times 20 mg/day p.o.
  • Topical: Apply 3 times/day thinly in the affected area.

Undesirable effects
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With systemic use danger of kidney dysfunction up to kidney failure, danger of thrombosis. With topical appl.: allergic skin reactions.

Standard concentration
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0.76-2% in ointments, solutions and gels.

Contraindication
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Topical appl. Paragroup allergy (ointment), application on mucous membranes or inflamed skin areas and open wounds.

Trade names
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Reparil, Venostasin, Essaven® Gel, Venoplant® Gel

Incoming links (2)

Horse chestnut extract; Saponins;