Results for "psoriasis"

...the mRNA expression of IL-17F, IL-12, IL-20 and IL-22, which are involved in the immune response to psoriasis. Allicin has also been shown to reduce the infiltration of CD3+, MPO+ and F4/80+ cells in psoriatic...

...t was found that aloe polysaccharide (20, 40, and 80 µg/mL for 24 hours) could be a useful agent in psoriasis, as evidenced by the inhibition of TNF-α levels and IL-8 and IL-12 protein expression in the human...

...nstrable).Pityriasis amiantacea: (Oily scaling covering the scalp; hair can be pulled out in tufts).Psoriasis capitis: (here the plaque-like psoriasis capitis is less responsible than the diffuse so-called seb...

...(see below anal eczema contact allergic). It is important to exclude hemorrhoidal disease, inverse psoriasis and atopic diathesis (see differential diagnosis below). Differential diagnosis Frequently:Psoriasi...

...olvement (oral and genital mucosa) in 20% of patients. Healing without scarring.An association with psoriasis is present in 1/3 of patients.The extent to which esophageal carcinomas are associated with the cli...

...decades (Castro-Giner F et al. 2009). Some regions correspond closely with the gene loci found for psoriasis (3q21), indicating that these genes have a general influence on "skin inflammation". Chronic inflam...

Calcitriol Definition Active metabolite of vitamin D3. Indication Mild to moderately severe psoriasis vulgaris of the plaque-type with an extension of < 35% of the body surface. Dosage and method of...

...ltures, chemerin is significantly downregulated by IL-17 and IL-22, important cytokines involved in psoriasis, while it is upregulated by the acute-phase cytokines oncostatin M (seeoncostatin M receptor below)...

...red to the normal population); vitiligo (3.5-fold increased risk compared to the normal population; psoriasis vulgaris (1.4-5-fold increased risk compared to the normal population). Laboratory Antinuclear anti...

...explained; reactive inflammatory epidermal hyperplasia is under discussion; increased occurrence in psoriasis! Manifestation Occurs in middle-aged and older patients. Localization Clinic 0.5 to 2 cm in size, o...

...the NLRP3 inflammasome, but not for the NLRC4 or AIM2 inflammasome (Yin H et al. 2018).Curcumin in psoriasis: Several recent studies have reported that curcumin can reduce oxidative stress in psoriasis lesion...

...in and systemic glucocorticoids.According to single case reports ( off-label use) well effective in psoriasis vulgaris, pemphigus vulgaris, psoriatic arthritis, graft-versus-host disease, ulcerative colitis, H...

...czema. Serum levels of human beta-defenin-2 are elevated in correlation to the activity and PASI of psoriasis (Abdelmaksood R et al. 2013). This finding is also not detectable in patients with atopic eczema. S...

Dithranol Definition Antipsoriatic. Indication Psoriasis vulgaris, alopecia areata. Limited indication Pregnancy (1st trimester), lactation, pustular psoria...

...(CD8) directed against melanocytes through the Th1/TH17 pathway drive this autoimmunologic process. Psoriasis and dupilumab: The blockade of IL-13/IL-4 by dupilumab can trigger the occurrence of psoriasis. Thi...

...tes. Superimposed orthokeratosis. Diagnosis Differential diagnosis Erythema anulare centrifugum-likepsoriasis: Rare, mild special form of pustular psoriasis generalisata (Zumbusch type) with the formation of c...

...HC complexes (pMHC) and present antigens directly to T cells(Buzas EI et al. 2023).EVs, obesity and psoriasis: In obese patients, EV levels in peripheral blood are significantly higher than in healthy individu...

...es may include cumulative toxic hand eczema/foot eczema, contact allergic eczema, atopic eczema and psoriasis palmaris et plantaris. S.a.u. occupational dermatoses. Clinic Hyperkeratotic-rhagadiform hand and f...

...tinguished from a bullous pemphigoid by its distribution pattern. Erythema anulare centrifugum-like psoriasis: Rare, mild special form of pustular generalized psoriasis (Zumbusch type) with the formation of ch...

...ous candidiasis but also to staphylococcal infections (see below chronic mucocutaneous candidiasis).Psoriasis and psoriatic arthritis (Villalpando-Vargas FV et al. 2021). Literature Joob B et al (2020) Psorias...

...ore associated with various diseases. For example, it has been postulated that auto-inflammation in psoriasis could be related to the recognition of its own DNA by AIM2 (Broz P et al. 2016). In addition, the a...

...of epidermal keratinocytes in psoriatic skin lesions. In addition, IFN-κ was detected in sera from psoriasis patients, but not in sera from normal individuals and atopic dermatitis (Li Y et al. 2019).In wound...

...an unregulated production of inflammatory cytokines, and clinically to severe generalized pustular psoriasis (Marrakchi S et al. 2011).In primary Sjögren's sydrome, elevated serum and tissue levels of IL-36al...

...with a JAK3 mutation. Leuk Lymphoma 60: 1626-1631.Kvist-Hansen A et al.(2020) Systemic Treatment of Psoriasis with JAK Inhibitors: A Review. Dermatol Ther (Heidelb) 10:29-42.Luo W et al.(2020) Targeting JAK-ST...

...ble to inhibit keratinocyte proliferation and vascular endothelial growth factor(VEGF) secretion in psoriasis. Keratinocytes treated with KRT16-siRNA and KRT16-siRNA + PD98059 showed decreased KRT16, p-ERK1/2...