Calcitriol
Definition
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Active metabolite of vitamin D3.
Indication
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Mild to moderately severe psoriasis vulgaris of the plaque-type with an extension of < 35% of the body surface.
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Dosage and method of use
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Ointment: Apply 2 times/day to the affected areas of skin (max. 35% of the body surface, max. 30 g ointment/day, max. for 6 weeks) Calcitriol can be used in the intertriginous area and with caution also on the face.
Standard concentration
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0.0003% in ointments.
Undesirable effects
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After application of Silkis 3 μg/g ointment, skin irritation (redness, itching) was observed to a small extent. Such skin irritations are usually temporary in nature.
Interactions
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Calcium preparations, salicylic acid, peeling agents, astringents, other irritant products: Increased skin irritation possible.
Contraindication
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Pregnancy, lactation, children and adolescents < 18 years, extensive application (> 35% KO), psoriasis punctata, pustular psoriasis; diseases of the calcium metabolism, severe liver and kidney diseases
Preparations
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Silkis 3 μg/g Ointment; Rocaltrol
Patientinformation
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Wash your hands after use to avoid transfer to the facial skin and other non-diseased skin areas! Do not add substances that increase skin absorption. Do not use an occlusive dressing!
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Prof. Dr. med. Peter Altmeyer