Dithranol
Synonym(s)
Dithranol ointment 005/01/025/05/1 or 2% without or with salicylic acid 2% (NRF 11.51.); Ingram Paste; Ingram-Paste washable; Washable dithranol ointment 005/01/025/05/1 or 2% without or with salicylic acid 2% (NRF 11.52.)
Definition
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Indication
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Limited indication
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Pregnancy (1st trimester), lactation, pustular psoriasis and other exudative forms of psoriasis.
Standard concentration
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0.05-3% in creams, ointments or pastes (for stabilization mostly in combination with salicylic acid) in increasing concentration. Apply 1-2 times/day to the affected areas and wash off after 10-60 minutes. Increase the concentration depending on the local irritation approx. every 3 days.
Undesirable effects
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Erythema, brown discoloration of the skin, hair discoloration (in blonde or gray hair), contact dermatitis.
Contraindication
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Use on the eye or mucous membranes, hypersensitivity to the active substance.
Recipe(s)
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Dithranol-Vaseline 0,05/0,1/0,25/0,5/1 or 2% without or with salicylic acid 2%
Ingram paste containing dithranol
Dithranol varnish I and dithranol varnish II
Dithranol ointment, washable 0.05/0.1/0.25/0.5/1 or 2% without or with salicylic acid 2%
Dithranol-macrogol ointment 0.25/0.5/1 or 2% (NRF 11.53.)
Dithranol-containing Ingram ointment washable
Dithranol zinc paste, soft 0,05/0,1/0,25/0,5/1 or 2% (NRF 11.56.)
Preparations
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Micanol, Psoralon (combination preparation with salicylic acid), Psoradexan mite/forte cream (combination preparation with urea)
Note(s)
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In intertriginous spaces apply dithranol in paste base, one concentration level lower than the rest of the Integument. The concentration of dithranol can be increased according to the skin condition.
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Prof. Dr. med. Peter Altmeyer
