Results for "psoriasis"

...ation and binding to the p40-kappaB sequence (D'Ambrosio D et al. 1998) Indication Mild to moderate psoriasis vulgaris of the plaque type with an extension of < 30% of the body surface. Dosage and method of...

...7 bindet spezifisch an den Chemokinrezeptor 10 (CCR10). Der CCR10-Rezeptor wird von Lymphozyten bei Psoriasis exprimiert. Studien an einem ähnlichen Mausprotein deuten darauf hin, dass diese Protein-Rezeptor-I...

...d, if necessary, the entire integument should be examined (e.g. in atopic diseases and in suspected psoriasis). If the vulva is to be assessed in more detail, vulvoscopy is recommended, which allows examinatio...

...ns have also been described in M.Darier, pityriasis rubra pilaris, mycosis fungoides, erythrodermic psoriasis, M. Grover . Some cases have been observed during treatment with vemurafenib and other biologics. O...

...lizumab. JDDG 9: 834Farewell M et al (2003) A novel target T-cell modulator, Efalizumab, for plaque psoriasis. N Engl J Med 349: 2004-2013Merckserono (2009) Important announcement. Drug safety. germany @mercks...

...a mycological exclusion diagnosis is recommended.If the clinical picture indicates the presence of psoriasis, histological confirmation of the diagnosis should be sought, as this is essential for long-term tr...

...Henoch purpura (Mani LY et al. 2015). Complicatively, IgA nephropathy (IgAN) may be associated with psoriasis (often severe) (Garces CC et al. 2021). Laboratory Non-selective proteinuria (usually <3g/day) a...

...ase, the presence of extra-articular manifestations or rheumatoid factor (RF) and family history of psoriasis or HLA-B27-associated diseases, six defined JIA categories are distinguished, including oligoarthri...

...NF-α and thus prevent the release of IL-1 and IL-6. They are used to treat chronic diseases such as psoriasis vulgaris, psoriasis arthropathica, rheumatoid arthritis, Crohn's disease. Cytokine antibody (usteki...

...complexed with IL-20R2. Occurrence It has been shown that IL-22 is involved in the pathogenesis of psoriasis. For example, IL-22 can inhibit the differentiation of keratinocytes and induced psoriasis-like cha...

...pidermis.Thus, deletion of two members, LCE3B and LCE3C (LCE3B/C-del) has been shown to be a common psoriasis risk factor that interacts with the major psoriasis risk gene HLA-C*06. LCE3A is directly adjacent...

...-25, all of which are essential for lymphocyte homing. Therapy LFA1 antibodies for the treatment of psoriasis: For example, efalizumab, a humanized antibody fragment that specifically blocks the α-subunit of L...

...itchy nodules and lumps Pityriasis rosea (exanthematic with eczematoid scaling, primary medallion) Psoriasis guttata (exanthematic with characteristic scaling, often accompanied by infection)Eczematid-like pu...

...lls and CD8+ cytotoxic cells. It has broad significance in inflammatory pathogenetic pathways (e.g. psoriasis, the systemic scleroderma). In psoriasis, LL-37 is upregulated. In wound healing, the antimicrobial...

...trosylation of cytoplasmic target proteins such as PTGS2/COX2. NO is involved in inflammation (e.g. psoriasis/ Ormerod AD et al. 1998), promotes the synthesis of proinflammatory mediators such as IL6 and IL8 (...

...es. As the disease progresses, acral skin and bone atrophies, dystrophy or loss of nails may occur. Psoriasis vulgaris: With psoriatic onychodystrophy; rarely isolated nail infestation; usually other stigmata...

...ymmetric (zoster; nevus flammeus, cutaneous mosaics; other skin infections)preferentially extensor (psoriasis vulgaris)preferentially flexural (atopic eczema, lichen (ruber) planus)arranged in the Blaschko lin...

...emotherapy. S.u. PUVA-therapy and KUVA-therapy. Indication Among other things for the treatment of: Psoriasis parapsoriasis en plaques Pruritus prurigo simplex subacuta Mycosis fungoides (erythema and plaque s...

...inhibitors and steroids. However, this could not be confirmed in a subsequent study. In the case of psoriasis inversa, clinical improvements after topical application of Pimecrolimus ( off-label-use) (see calc...

Nail pitting due to psoriasis Definition Superficial, fine, barely 0.1 cm large, round or oval, punctate depressions of the nail...

...ing skin disease of unexplained etiology and pathogenesis, which was classified in the group of parapsoriasis diseases, i.e. psoriasis-like diseases, by the work of Brocq (1902). (Note: this classification can...

...ARCAL1 geneImmunodeficiency 10 and NFKB2 defect (vitiligo, autoimmune thyroiditis, endocrinopathies)Psoriasis and psoriasiform exanthemaIL10 defects/mutation in IL10RA/IL10RBICF syndrome/mutation in DNMT38/ ZB...

...8.Lis-Święty A et al. (2022) Proactive therapy: new perspectives for long-term topical treatment of psoriasis. Dermatol Ther. ;35: e15364Lavaud J et al (2020) Proactive treatment in childhood psoriasis. Ann De...

...otein family. It was first identified as an 11.4 kDa cytoplasmic and secreted protein isolated from psoriasis-affected skin that can be induced in cultured squamous cells.It was later revealed to be expressed...

PSORS3 Definition PSORS3 (PSORS3 stands for: Psoriasis Susceptibility 3) is a genetic locus on chromosome 4q associated with psoriasis. Seven susceptibili...