Proactive therapy

Continuation of anti-inflammatory therapy, e.g. in atopic dermatitis, usually with the calcineurin inhibitors Tacrolimus or Pimecrolimus, beyond the healing stage. Previously affected eczema sites are treated 1-3 x week for several months.

In the meantime, proactive therapy e.g. with vitamin D analogues as monotherapy or in combination with local steroids (calcipotriol/bethamethasone dipropionate foam) is also propagated for the treatment of psoriatic plaques.

1. Wollenberg A. et al. (2018) Consensus-based European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children: part I. J Eur Acad Dermatol Venereol 32:657-668.
2. Lis-Święty A et al. (2022) Proactive therapy: new perspectives for long-term topical treatment of psoriasis. Dermatol Ther. ;35: e15364
3. Lavaud J et al (2020) Proactive treatment in childhood psoriasis. Ann Dermatol Venereol. 147: 29-35.
4. Ito K et al (2016) Proactive treatment with calcipotriol reduces recurrence of plaque psoriasis. J Dermatol. 43:402-405
5. Körber A et al (2016) Topical therapy for psoriasis vulgaris - a treatment pathway. J Dtsch Dermatol Ges. 17 Suppl 4:3-14.