Angelicae radix

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 04.09.2021

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Synonym(s)

Angelica; Angelica root

Definition
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Angelica root or angelica is a drug used as a herbal medicine with digestive, antispasmodic and antiflatulent effects. Angelicae radix is obtained from the dried roots of the plant Angelica archangelica the angelica.

HPMC: not processed.
ESCOP monograph: dyspeptic complaints, mild abdominal cramps, delayed digestion, flatulence and bloating; loss of appetite, bronchitis;
Commission E monograph: loss of appetite; digestive complaints such as mild gastrointestinal cramps, bloating, flatulence.

Ingredients
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Angelicae radix contains essential oil (0.5 to 1%) with pentadecanolide, linear furanocoumarins such as ammoidin, imperatorin, angular furanocoumarins such as angelicin and archangelicin. Furthermore tanning agents, phytosterols and sugars.

Effects
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Angelicae radix has spasmolytic and cholagogue effects and promotes the secretion of gastric juice. It also has a mild antidepressant, analgesic and antimicrobial effect.

Field of application/use
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Angelicae radix is used for indications such as loss of appetite and dyspeptic complaints such as a feeling of fullness, gastrointestinal cramps, anorexia or flatulence.

Undesirable effects
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The furanocoumarins in the drug cause an increased light sensitivity; already at low UV light exposure a dermatitis solaris may occur.

Gloves should be worn when harvesting the angelica root and the herb of the plant. Direct contact with the eyes should also be avoided.

Recipe(s)
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The fixed combination"angelica root+gentian root+caraway" positively monographed by Commission E consists of:

This combination of medicines is used for flatulence, loss of appetite and dyspeptic complaints.

The fixed combination of angelica root + gentian root + wormwood consists of:

stimulates the appetite, promotes the secretion of gastric juice and is used in cases of loss of appetite and dyspeptic complaints such as bloating and flatulence.

Literature
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  1. Chang YX et al. (2013) Simultaneous determination of scopoletin, psoralen, bergapten, xanthotoxin, columbianetin acetate, imperatorin, osthole and isoimperatorin in rat plasma by LC-MS/MS for pharmacokinetic studies following oral administration of Radix Angelicae Pubescentis extract.J Pharm Biomed Anal 77:71-75.
  2. Schilcher H (2016) Leitfaden Phytotherapie, Urban & Fischer Verlag Munich, pp. 53 f.
  3. https://arzneipflanzenlexikon.info/angelica.php