Macrolide antibiotics

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Antibiotics with predominantly bacteristatic action against Gram-positive cocci and rods and Gram-negative cocci, as well as atypical and/or intracellular bacteria such as chlamydia, mycoplasma and spirochetes. An essential disadvantage of macrolide antibiotics is the rapid development of resistance in Gram-negative cocci.

Pharmacodynamics (Effect)
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Reversible attachment to 50S subunit of ribosomes and inhibition of protein synthesis. Macrolide antibiotics include:


Last updated on: 29.10.2020