Macrolide antibiotics

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 22.05.2025

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Synonym(s)

Macrolides

Definition
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Antibiotics with a predominantly bacteriostatic effect against gram-positive cocci and rods and gram-negative cocci as well as atypical and/or intracellular bacteria such as chlamydia, mycoplasma and spirochetes. A significant disadvantage of macrolide antibiotics is the rapid development of resistance in gram-negative cocci.

Pharmacodynamics (Effect)
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Reversible attachment to the 50S subunit of ribosomes and inhibition of protein synthesis. The macrolide antibiotics include:

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Last updated on: 22.05.2025