Spiramycin

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Half-life
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3–4 h

Spectrum of action
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According to erythromycin, no effect on H. influenzae. In high dosage effectiveness against Toxoplasma gondii.

Indication
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Tonsillitis, pharyngitis, otitis media, skin and soft tissue infections, toxoplasmosis, especially during pregnancy.

Dosage and method of use
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  • General infections:
    • Adults: 6 million IU/day p.o. in 2-4 ED. For severe infections up to 12 million IU/day
    • Infants and children < 6 years.: 4 times/day 40.000 IU/kg KG p.o.
  • Toxoplasmosis:
    • adults: 9 million IU/day p.o. in 2-4 ED.
    • children in 1st year: 300 000 IU/kg bw.

Undesirable effects
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S.u. Erythromycin. Less severe gastrointestinal side effects than erythromycin.

Preparations
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selectomycin, rovamycins

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Last updated on: 29.10.2020