
Acrokeratosis paraneoplastic L85.1
Acrokeratosis paraneoplastic: Disseminated, cup-like, brown-yellowish, partly disseminated, partly grouped, flat hyperkeratotic papules.

Naevus melanocytic common D22.-
Nevus melanocytic common: multiple acquired melanocytic nevi (detailed picture).

Melanoma acrolentiginous C43.7 / C43.7

Keratosis palmoplantaris diffusa with mutations in KRT 9 Q82.8
Keratosis palmoplantaris diffusa circumscripta: Thick, waxy, yellowish, plate-like horny layer which covers the entire palm of the hand and also the sole of the foot. The mobility of the hands is restricted. Characteristically, the red seam of the affected groin skin shown here separates the infected skin from unaffected field skin.

Early syphilis A51.-
Syphilis Early syphilis: discreet , non-itching or painful, maculo-papular palmar syphilis

Hand and foot eczema, hyperkeratotic-rhagadiformes L24.9

Contact dermatitis toxic L24.-
contact dermatitis, toxic: overview picture: hyperkeratotic-rhagadiform eczema of the Palma in a 61-year-old, self-employed craftsman. for a long time eczema of the hands and fingers occurred again and again, partly also deep rhagades. occupationally there has been contact with tin-containing analogue paste (tin-containing soldering paste) for a long time. the temporal connection of the first manifestation with the use of the paste is given. on weekends the eczema heals very well, likewise it comes to complete remission during longer work-free intervals (holidays).

Dyskeratosis follicularis Q82.8
Dyskeratosis follicularis: Infestation of the palms of the hands; in central areas of the palm flat, common keratoses, at the ball of the thumb about 0.1-0.2 cm large, glassy papules.

Keratosis palmoplantaris diffusa with mutations in KRT 9 Q82.8
Keratosis palmoplantaris diffusa circumscripta: Thick, waxy, yellowish, plate-like horny layer that covers the entire palm of the hand and also the sole of the foot; the mobility of the hands is restricted.

Addison's disease E27.1
Addison's disease: the palms of the previously described patient. pigmentation of the palm lines as well as the finger wrinkles. hyperpigmentation at traumatized areas typical for Addison's disease (here: calluses)

Keratosis palmoplantaris diffusa with mutations in KRT 9 Q82.8
Keratosis palmoplantaris diffusa circumscripta: detailed view

Hand and foot eczema, hyperkeratotic-rhagadiformes L24.9

Early syphilis A51.-
Syphilis Early syphilis: psoriasiformes papular palmarsyphilid as partial manifestation of a generalized papular exanthema.

Early syphilis A51.-
Syphilis Early syphilis: a long-standing, distinct, locally psoriasiform papular palmar syphilis.

Fixed drug eruption L27.1
Drug reaction, fixed: recurrent course with acute itchy redness 1 day after taking ibuprofen (600 mg) due to rheumatoid complaints. After 2-3 days the acute symptoms subsided with the residual hyperpigmentation shown here. The acute changes occurred strictly localized.

Keratosis palmoplantaris diffusa with mutations in KRT 9 Q82.8
Keratosis palmoplantaris diffusa circumscripta. 2-year-old boy has a chronic, congenital, smooth, evenly distributed, waxy thickened and yellowish discolored plaque formation of both palms. No symptoms. It is an autosomal dominant inherited palmoplantar cornification disorder.

Keratosis palmoplantaris diffusa with mutations in KRT 9 Q82.8
Keratosis palmoplantaris diffusa circumscripta, congenital, massive, evenly distributed, waxy corneal layer in adults, no symptoms!

Pustulosis palmaris et plantaris L30.2
Pustulosis palmaris et plantaris: acutely occurring, disseminated, 0.2-0.4 cm large, smooth yellowish pustules next to older, dried brown spots; neither history nor clinical evidence of psoriasis.

Acromegaly E22.0
Acromegaly: 43-year-old patient with known acromegaly. Noticeable increase in size of the lower extremities. Simultaneous development of excessive varicosis with consecutive chronic venous insufficiency (CVI).

Contact dermatitis toxic L24.-
Contact dermatitis toxic: General view: Hyperkeratotic-rhagadiform contact dermatitis with extensive hyperkeratotic plaques and single rhagades on the right palm of a 63-year-old metal worker.