Stomatitis, drug-induced - Altmeyers Encyclopedia

Definition
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Drug-induced inflammation of the oral mucosa, also known as gingivostomatitis acuta.

Clinic
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Sharply jagged, hyperemic bordered, aphthous ulcerations, especially in the folds of the neck after taking methotrexate, 5-fluorouracil or other cytostatic drugs. Large ulcerations after gold or actinomycin D therapy.

General therapy
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Avoid the triggering drugs.

External therapy
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Oral hygiene, rinsing with antiseptic and anti-inflammatory solutions such as 0.1-0.2% chlorhexidine solution R045 or tormentil astringent R255, ratanhia-myrrh astringent R210, camomile, sage, myrrh or other plant extracts (e.g. gingivitol, camillosan, salus sage trp.). Possibly anaesthetic solutions before meals (e.g. Acoin solution, periodontal mouth ointment). S.a.u. Stomatologika.