Sildenafil

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Indication
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Impotentia coeundi (erectile dysfunction).

Dosage and method of use
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Medication required: 50-100 mg once/day about 1 hour before sexual intercourse. Initial dose 50 mg, in patients > 65 years of age 25 mg p.o.

Note ! The effect lasts up to 4-6 hours after ingestion!

Undesirable effects
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  • Very often (> 10%): headache, flush.
  • Frequently (1-10%): Dyspepsia. Visual disturbances.

Interactions
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Nitrates, NO-donors (e.g. amyl nitrite, molsidomine): Potentiation of the blood pressure lowering effect.

Contraindication
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Not with women and Pat. < 18 LJ. Contraindicated also in comedication with CYP-3A4 inhibitors such as cimetidine, erythromycin, ketoconazole, saquinavir.

Preparations
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Viagra

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Last updated on: 29.10.2020