Purpura (overview) D65-D69

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 17.12.2023

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Synonym(s)

hemorrhage of the skin; Skin bleeding

Definition
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The term purpura in the narrower sense refers to the seeding of small spots of blood in the skin. Skin hemorrhages (hemorrhages) are a clinical phenomenon. Purpura is characterized by localized or disseminated, small-spotted or extensive, red, blue, blue-green or yellow-brown (diascopically non-blanchable) spots or palpable elevations (shades due to bleeding of different ages). Purpura can be triggered by a variety of causes.

Purpura can be flat(spot) or elevated(papule = palpable purpura), inflammatory (vasculitis) or non-inflammatory (e.g. due to a vasculopathy).

In a broader sense, independent diseases are also referred to as "purpura", which are associated with hemorrhages in the skin (e.g. purpura pigmentosa progressiva; purpura Schönlein-Henoch).

Classification
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A distinction is made according to shape and size:

Etiopathogenesis
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Etiologically, a vascular (vessel wall damage) can be distinguished from a purpura due to coagulation disorders.

Clinical features
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Literature
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  1. Cines DB, Blanchette VS (2002) Immune thrombocytopenic purpura. N Engl J Med 346: 995-1008
  2. Hundeiker M et al (1977) Dermatological purple forms as early and late allergic reactions. Act Dermatol 3: 39-48
  3. Moake JL (2002) Thrombotic microangiopathies. N Engl J Med 347: 589-600

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Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 17.12.2023