Purpura (overview) D65-D69

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 23.04.2022

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Synonym(s)

hemorrhage of the skin; Skin bleeding

Definition
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The term purpura is used in a narrow sense synonymously for bleeding into the skin. Skin hemorrhages are a clinical phenomenon in which there are leaks of erythrocytes into the dermal tissue. Skin hemorrhages can be acute or chronic. They are characterized by localized or disseminated, small-spotted or patchy, red, blue, blue-green, or yellow-brown (diascopically not pushable away) spots or palpable elevations (hues due to hemorrhages of different ages). Purpura can be triggered by a variety of causes.

Purpura may be flat (spot) or elevated (papule = palpable purpura), inflammatory (vasculitis) or noninflammatory (e.g., due to vasculopathy).

In a broader sense, independent diseases are also called "purpura", which are associated with hemorrhages into the skin (e.g. purpura pigmentosa progressiva; purpura Schönlein-Henoch).

Classification
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A distinction is made according to shape and size:

Etiopathogenesis
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Etiologically, a vascular (vessel wall damage) can be distinguished from a purpura due to coagulation disorders.

Clinical features
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Literature
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  1. Cines DB, Blanchette VS (2002) Immune thrombocytopenic purpura. N Engl J Med 346: 995-1008
  2. Hundeiker M et al (1977) Dermatological purple forms as early and late allergic reactions. Act Dermatol 3: 39-48
  3. Moake JL (2002) Thrombotic microangiopathies. N Engl J Med 347: 589-600

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 23.04.2022