DefinitionThis section has been translated automatically.
Characteristic histological pattern of diffuse superficial dermatitis detectable in etiopathogenetically different inflammatory dermatoses.
The interface dermatitis is characterized by an epitheliotropic, lymphocytic infiltrate which leads to chronic, vacuolar damage of the basal keratinocytes (and melanocytes) at the epidermis, with signs of apoptosis and its histomorphologically detectable consequences.
The term "lichenoid dermatitis" is also used synonymously with the term "interface dermatitis". Terminologically this refers to the lichen planus and is to be understood as a subgroup of interface dermatitis.
ClassificationThis section has been translated automatically.
Diseases whose histological substrate is characterized by interface dermatitis (varies according to El Shabrawi-Caelen and Soyer):
- Interface dermatitis - Lichen planus-like interface dermatitis with a dense ligamentous infiltrate and premature terminal differentiation with distinct stratum granulosum:
- Interface dermatitis with acute cytotoxic damage (erythema-exudativum-multiforme-like interface dermatitis); distinct basal-hydropic damage of the surface epithelium with necrotic keratinocytes in all epithelial layers:
- interface dermatitis with psoriasiform epidermal hyperplasia:
- Interface dermatitis with irregular epidermal hyperplasia:
- Interface dermatitis with epidermal atrophy (with only minor inflammatory infiltrates):
HistologyThis section has been translated automatically.
The signs of apoptosis of keratinocytes are described as "dyskeratotic" or "single cell necrosis". Eosinophilic corpuscles with little structure remain at the dermo-epidermal junction zone even as:
- cytoid corpuscles
- hyaline bodies
- Colloidal body
LiteratureThis section has been translated automatically.
- El Shabrawi-Caelen L, Soyer H-P (2003) Inflammatory dermatoses of the dermoepidermal junction (interface dermatitis). In: Histopathology of the skin. Kerl H et al (Ed.) Springer Verlag, Berlin Heidelberg New York, S. 117