DefinitionThis section has been translated automatically.
Localized, encapsulated inflammation in the epidermis, hair follicles, in eccrine or apocrine sweat glands, in the dermis and/or subcutis, caused by pus-inducing substances or pathogens (bacteria or fungi), accompanied by tissue melting, and melting centrally after 4-5 days.
Pus is the constellation of neutrophilic granulocytes, cellular debridement, and liquefied tissue. Abscess is the name given to the purulent, fluctuant, cutaneous or subcutaneous formation of a cavity. Epidermal or infundibular accumulations of pus are called pustules or, in the minus variant, microabscesses (e.g. Munro microabscess in psoriasis vulgaris).
Notice. The microabscess named after Pautrier, which consists of lymphocytes and not neutrophilic granulocytes, is to be understood as a misnomer.
PathogenThis section has been translated automatically.
Mostly staphylococci (especially Staphylococcus aureus), more rarely gram-negative germs (E. coli, Proteus mirabilis) or mixed flora. The typical characteristics are determined by the pathogenic properties of the pathogens. Staphylococci form the enzyme coagulase, which activates the coagulation and slows down the spread of the inflammation in the interstitium.
Dead parasites or their remains are further causes of abscess formation.
Fungi can also lead to abscesses in rare cases.
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Clinical featuresThis section has been translated automatically.
Complication(s)This section has been translated automatically.
TherapyThis section has been translated automatically.
Bacterial follicular and non follicular pustules are treated locally with antiseptic and internally with antibiotics. Dermal abscesses must be sufficiently incised and drained; penicillinase-resistant penicillin, possibly after antibiogram.
Alternative: Clindamycin 3x300mg/day p.o. for 10 days
Alternative: Trimethoprim-Sulfmethoxazole 2x 160TMP/800 SMXmg/day p.o. over 10 days
LiteratureThis section has been translated automatically.
- Miller LG et al (2015) Clindamycin versus trimethoprim-sulfamethoxazole for uncomplicated skin infections.N Engl J Med 372:1093-1103
Incoming links (24)Abscess, cold; Abscess, periproctitic; Acne aggregata; Ammonium bituminosulfonate dark; Ammonium bituminosulfonate dark; Ammonium bituminosulfonate dark; Amoeba abscess; Callus abscess; Carbuncle; Daptomycin; ... Show all
Outgoing links (5)Antibiogram; Munro microabscess; Pauterian microabscesses; Penicillin; Staphylococcal infections;
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