Lower leg eczema, periulcerous or paratraumatic L24.9

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Toxic contact eczema due to maceration of the skin by secretion of a venous leg ulcer.

Complication(s)
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Contact sensitisation against local therapeutic agents (often antibiotics, e.g. chloramphenicol, neomycin, fucidic acid).

General therapy
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The treatment focuses on preventing further maceration of the ulcer environment by the ulcer secretion. Secondary contact allergies usually occur, which must also be prevented or treated.

External therapy
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No polypragmasia, as sensitisation often occurs. If possible, epicutaneous testing (ointments, ointment supplements, disinfectants, local anaesthetics, antibiotics) before starting therapy again, see Table 1. Cleaning: Careful cleaning of the periulcerous area. Removal of ointment residues with oils, e.g. Oleum olivarum or detachment with physiological saline solution or Ringer's solution. Cleansing baths for very dry skin with addition of a bath oil (e.g. Balneum Hermal oil bath, Linola fat oil bath). It is important to avoid irritation of the ulcer environment by the ulcer secretion, e.g. by covering the ulcer environment with zinc paste (Pasta zinci R295 ), cover paste R001 or R002, pure Vaseline or an indifferent fat cream. Also a soft paste such as Pasta zinci mollis/Ungt. molle can be helpful to cover and care for the chronically scaling eczema in addition to ointments and fatty ointments.

Pyodermic: Baths with addition of a disinfectant such as potassium permanganate (light pink) or polyvidon iodine solution (e.g. R203, Betaisodona Lsg.).

Acute, non-wetting: Hydrophilic creams (type O/W) like Unguentum emulsificans aquosum or base cream (DAC), lotions (e.g. Lotio alba) or emulsions (Ungt. Cordes) have anti-inflammatory and cooling effects.

Weeping: Moist and greasy damp compresses for 2-3 days (otherwise excessive drying out). Short-term glucocorticoid-containing external preparations in an indifferent base e.g. 0.1% triamcinolone ointment or 0.25% prednicarbate (e.g. Dermatop ointment/fatty ointment) in combination with moist compresses with e.g. 0.9% saline solution or polihexanide (Prontosan, Serasept, Prontoderm). Brushing with aqueous, disinfectant solutions for drying is also possible.

Dry: Exteriors with a low fat content, Vaseline alb. or fatty ointments. In the initial phase of the acute eczema, short-term external preparations with added glucocorticoids, e.g. 0.1% triamcinolone ointment (e.g. Triamgalen or a 0.1% triamcinolone acetonide ointment) or 0.5-1.0% hydrocortisone cream (e.g. Hydro-Wolff, R120 ) or 0.25% prednicarbate (e.g. Dermatop ointment/fatty ointment). It has proved to be effective to intensify the lipid replenishment by a short-term occlusive treatment by applying a plastic foil (e.g. household foil) for 8-12 hours. Powders, shaking mixtures and/or moist compresses are not indicated here due to their drying effect.
The combination of a fatty ointment with moist compresses can also be used for a short period of time in crusty and/or squamous chronic forms of eczema.
When using special formulations with heparin/heparinoid additives in pastes that are suitable for promoting blood circulation around the ulcer margins, caution is always advised against possible sensitisation.

Tables
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Sensitization in case of leg ulcer and/or lower leg eczema

Active ingredient groups

Active ingredients

Ointment bases

e.g. wool wax alcohols, Peru balsam

Disinfectants and preservatives

e.g. quinoline, isothiazoles, parabens, sorbic acid

Antibiotics

e.g. neomycin, gentamicin, bacitracin

Local anaesthetics

e.g. benzocaine, pantocaine

Glucocorticoids

Literature
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  1. Daroczy J (2002) Antiseptic efficacy of local disinfecting povidone-iodine (Betadine) therapy in chronic wounds of lymphedematous patients. Dermatology 204(Suppl1): 75-78
  2. Lindemayr H et al (1985) Lower leg eczema and contact allergy. dermatologist 36: 227-231
  3. Tronnier H (1996) Phased therapy of lower leg eczema. Vasomed 2: 82-92

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Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020