Sabale extract

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 03.02.2025

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Synonym(s)

Saw Palmetto; Saw palmetto plant; serenoa repens; serona serrulata

Definition
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Extract from the saw palmetto, or the fruits of the saw palmetto, Sabalis serrulatae fructus.

Spectrum of action
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Extracts from Fructus Sabalis serrulatae contain: essential and fatty oils with 75% fatty acids such as caproic, capric, lauric, palmitic and oleic acids. Furthermore free or esterified beta-sitosterol, flavonoids (rutin, rhoifolin and isoquercitrin) and various polysaccharides. polysaccharides.

Aqueous and alcoholic extracts have an anti-inflammatory effect

Lipophilic extracts have an anti-androgenic effect (without estrogenic effect).

Ethanolic saw palmetto extracts are mixed with other phytoextracts (especially pumpkin seed extracts, nettle root extracts) and used for benign prostatic hyperplasia in stages I to II (note: study results are inconsistent)

Dermatologically, sabal extracts are used for acne and androgenetic alopecia.

Cosmetics: Serona serrulata extract is widely used in cosmetic formulations.

Preparations
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Keracnyl®

Literature
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  1. Herman A et al (2016) Mechanism of action of herbs and their active constituents used in hair loss treatment. Fitoterapia 114:18-25.
  2. Wessagowit V et al. (2015) Treatment of male androgenetic alopecia with topical products containing Serenoa repens extract. Australas J Dermatol 57:e76-82.
  3. Yin J et al (2016) Inhibitory Activities of Phenolic Compounds Isolated from Adina rubella Leaves Against 5α-Reductase Associated with Benign Prostatic Hypertrophy. Molecules doi:10.3390/molecules21070887.