Dipentene (dilimonene)

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

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Last updated on: 18.04.2024

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CAS No:138-86-3; Dipentene; INCI designation: Limonene; Lemons

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Limonene is a natural product found in essential oils and spices. Dipentene is used as a flavoring and fragrance. It is also used in printing inks and in the paint and varnish industry. In a larger collective of epicutane-tested patients with a corresponding medical history, 5-0% showed a positive patch test reaction to oxidized limonene (test formulation: 0-3% in Vaseline) and 5-9% to oxidized linalool (1-0% in Vaseline). The substance can be found in the epicutaneous test series at: other fragrances; see below. Other fragrances (epicutaneous test series)

The DKG has so far tested the mixture dipentene, which consists of d-limonene and 1-limonene 2.0% in Vaseline. This form of application is no longer available as a test substance in Germany. In this respect, a 2% concentration of d-limonene in Vaseline is now recommended (as of 2016). A limitation of the diagnostic value is not to be expected, especially since the actual allergens are oxidation products of limonene.

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