Agrimoniae herba

Authors: Prof. Dr. med. Peter Altmeyer, Prof. Dr. med. Martina Bacharach-Buhles

All authors of this article

Last updated on: 29.10.2020

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Synonym(s)

Agrimony; Braids; Burdock; cinquefoil; Field cabbage; Folia Agrimoniae; Greek liverwort; Herba Agrimoniae; Herba Eupatoriae; Ottermint; Rockroot; Rock Root; Stubwort; Warbler; weed; Winchweed

Definition
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Agrimoniae herba, also known as agrimony herb, is a drug that has been positively monographed by Commission E and is used in herbal medicinal products for the treatment of, inter alia, diarrhoea and inflammation of the mucous membranes. The drug consists of the shoots of the above-ground plant that are cut and dried during the flowering period.

Ingredients
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Agrimoniae herba contains 4% to 10% catechin tanning agents (according to Ph. Eur. at least 2%), flavonoids, phenolic carboxylic acids and triterpenes, including ursolic acid.

Effects
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Agrimoniae herba relieves existing itching in inflammatory skin diseases (Commission E, ESCOP), has a mild anesthetic effect, also has astringent, antiphlogistic, bacteriostatic and antiviral effects.

Field of application/use
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Agrimony herb is used in accordance with the guidelines of Commission E for mild, non-specific and acute diarrhoea, mild inflammation of the skin and inflammation of the mouth and throat mucosa. According to ESCOP, WHO and HMPC monographs, agrimony herb is also used for external application as a compress or as an irrigation to support wound healing.

Dosage
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The daily dose of the drug agrimony lies between 3 and 6 g. In case of external use, use compresses with a 10% decoction several times a day.

Undesirable effects
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Photoallergic reactions possible after local application of the drug and subsequent UV exposure.

Contraindication
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There are no known contraindications.

Interactions
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There are no known interactions with other drugs. However, when used internally, it is possible that other drugs taken at the same time may be inhibited.

Literature
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  1. Bae H et al (2010) Inhibitory effect ofAgrimoniae
    Herba on lipopolysaccharide-induced nitric oxide and proinflammatory cytokine production in BV2 microglial cells. Neurol Res 32 Suppl 1:53-57.

  2. Granica S et al (2015) The phytochemical investigation of Agrimonia eupatoria L. and Agrimonia procera Wallr. as validsources
    of Agrimoniae herba--The pharmacopoeial plant material. J Pharm Biomed Anal 114:272-279.

  3. Qu D et al (2014) Synthesis and in vitro antineoplastic evaluation of silver nanoparticles mediated by Agrimoniae herba extract. Int J Nanomedicine. 9:1871-1882.https://www.ncbi.nlm.nih.gov/pubmed/24790429

  4. Schilcher H (2016) in: Guide to Phytotherapy, Urban & Fischer Verlag Munich, S. 233 f.