Lh

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

HCG (humanes Chorion-Gonadotropin); ICSH; ICSH (interstitiell cell stimulating hormone); interstitial cell stimulating hormones

Definition
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Glycoprotein hormone produced in the adenohypophysis, which predominantly controls the incremental (= hormonal) function of the gonads. Thus the Leydig's intermediate cells are continuously stimulated in men (testosterone production in the tests) and in women cyclically the ovulation and subsequently the function of the corpus luteum (estrogen and progesterone production). The release occurs analogous to FSH by pulsatile secretion of GnRH from the hypothalamus and is subject to an endogenous feedback mechanism.

General information
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Standard value: The values are measured in U/l.

Reference range for women (U/l)

  • Follicular phase: 2-6
  • Ovulation phase: 6-20
  • Luteal phase: 3-8
  • Postmenopause: >30

Reference range for men (U/l)

  • prepubertal: 0,2-0,8
  • Postpubertal: 0,8-8,3

LH increased:

  • LH increased (women): primary ovarian failure, germ cell tumors, terminal renal failure, pregnancy, ectopic pregnancy, polycystic ovaries
  • LH increased (men): primary testicular insufficiency, hypergonadotropic hypogonadism, androgen resistance syndrome

LH humiliated:

  • LH decreased (women): secondary ovarian failure due to hypothalamic hypophasic dysfunction (Kallmann syndrome, anorexia), ovulation inhibitor, sexual steroid substitution
  • LH humiliated (men): sec. testicular insufficiency, hypogoandotropic hypogonadism (hypophasia, hypothalamus), exogenous testosterone supply
  • Functional deficiency: high performance sport, serious diseases, malnutrition, anorexia nervosa

Literature
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  1. Backhaus BO et al (2003) Therapy of cryptorchidism: aspects for optimizing fertility. Urologist 42: W1265-1270
  2. Perkins GL et al (2003) Serum tumor markers. On Fam Physician 68: 1075-1082
  3. Schirren C, Leidenberger F, Stoll P (1980) The childless marriage. 1st edition, Deutscher Ärzteverlag Cologne

Outgoing links (2)

Fsh; Gnrh;

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Last updated on: 29.10.2020