Leydig cell insufficiency, postpubertal E23.0

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Androgen deficiency due to reduced pituitary LH/ICSH of unknown etiology; androgen-dependent strongly reduced fructose concentration in the ejaculate with strongly reduced fertility (see fertility disorder); otherwise normal male habitus, normal testicular size and normozoospermia.

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Hormone substitution with HCG (e.g. Predalon) 5000 IU/week i.m. and HMG (e.g. Menogon) 3 times/week 150 IU until normalization of fructose in the ejaculate. If necessary, testosterone substitution with testosterone nantate (e.g. Testoviron depot 50), initial 50 mg/month i.m., slowly increase dose within 1-2 years to 250 mg/month i.m.

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Last updated on: 29.10.2020