DefinitionThis section has been translated automatically.
X-linked recessive inherited disease caused by a dysfunction of the androgen receptor
ManifestationThis section has been translated automatically.
Only men are affected, women act as conductors. Manifestation between the ages of 20 and 40.
Clinical featuresThis section has been translated automatically.
Stress-related muscle cramps and fasciculations, then proximal muscle weakness, slow progression with development of bulbar symptoms (dysarthria, dysphagia). In 50% of cases gynecomastia, testicular atrophy with restriction of spermatogenesis and secondary impotentia gestandi; frequent increase of LH and FSH, only in one third decrease of serum testosterone. Commonly diabetes mellitus or subclinical glucose tolerance disorder.
TherapyThis section has been translated automatically.
Symptomatic, no causal therapy is known.
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Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer