Tuberculosis ulcerosa mucosae et cutis A18.4

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Contaminated tuberculosis; Mucosal ulcers tuberculous; Tuberculosis cutis orificialis; Tuberculosis miliaris ulcerosa mucosae et cutis; tuberculosis orificialis; Tuberculosis Tuberculosis; tuberculosis ulcerosa cachecticorum; Tuberculous mucosal ulcers; Ulcerous mucosal tuberculosis

Definition
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Autoinoculation in "open" visceral tuberculosis in the body orifices by excreted tubercle bacteria. The massive autoinoculation leads to miliary, rapidly disintegrating, very contagious nodules. Anergic reaction position.

Localization
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Mainly the oral cavity, lips and the corners of the mouth are affected, but also the orifice urethra and anus.

Clinical features
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Small, reddened, later ulcerous papules. Formation of soft, painful, superficial, purulent ulcerations surrounded by an edematous mucosa.

Laboratory
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The tuberculin reaction is negative. Numerous tuberculous bacteria are detectable in the smear.

Histology
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Exudative inflammation, necrosis, isolated tuberculoid granulomas.

Diagnosis
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Differential diagnosis
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Therapy
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Treatment of the underlying organ tuberculosis. Symptomatic local therapy corresponding to tuberculosis cutis luposa, see there.

Progression/forecast
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Overall unfavourable.

Literature
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  1. Chen Q et al (2019) Cutaneous tuberculosis: A great imitator. Clin Dermatol 37:192-199.
  2. Hodzic-Avdagic N et al (2003) Tuberculosis miliaris ulcerosa mucosae Dermatologist 54:360-362.

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020