Synonym(s)
HistoryThis section has been translated automatically.
Tabuenca 1981
DefinitionThis section has been translated automatically.
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Occurrence/EpidemiologyThis section has been translated automatically.
EtiopathogenesisThis section has been translated automatically.
ManifestationThis section has been translated automatically.
Acute phase: Women and men are affected equally often.
Chronic phase: Women are affected 6 to 10 times more often than men.
Clinical featuresThis section has been translated automatically.
Acute phase: 7-10 days after consumption fever, dyspnea due to interstitial pneumonia and pulmonary edema, gastrointestinal complaints.
Subacute phase: After about 2 months, nonspecific pruriginous skin lesions, maculopapular or urticarial erythema, arthralgias, myalgias.
Chronic phase: From the 4th month, in 10-15% of patients neuromuscular syndrome with scleroderma-like or poikiloderma-like skin manifestations. Furthermore, livedo reticularis, Raynaud's syndrome, Sjögren's syndrome, carpal tunnel syndrome, dysphagia or pulmonary hypertension may occur.
LaboratoryThis section has been translated automatically.
eosinophilia (>1000 plates/mm3). IgE elevation. In 35-80% of cases ANA is positive.
Differential diagnosisThis section has been translated automatically.
TherapyThis section has been translated automatically.
Symptomatic physical and external therapy (see also scleroderma, progressive systemic), causal therapy unknown. If only sclerotic skin changes are present (without systemic involvement), phototherapy with UVA1 (20 J/cm2, for 6-8 weeks, 4 times/week) or PUVA bath therapy.
In case of systemic involvement, proceed as in progressive systemic scleroderma.
Progression/forecastThis section has been translated automatically.
LiteratureThis section has been translated automatically.
- Bell S et al (1992) The toxic oil syndrome - an example of an exogenously induced autoimmune disease. dermatologist 43: 339-343
- Sanchez-Porro Valades P et al (2003) Toxic oil syndrome: survival in the whole cohort between 1981 and 1995 J Clin Epidemiol 56: 701-708
- Hubbard V et al (2003) Scleromyxoedema-like changes in four renal dialysis patients. Br J Dermatol 148: 563-568
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Incoming links (5)
Eosinophilic myalgie syndrome; Lung diseases, skin changes; Nephrogenic systemic fibrosis; Pseudoscleroderma; Toxic oil syndrome;Outgoing links (8)
Eosinophilic myalgie syndrome; Erythema; Livedo reticularis; Pseudoscleroderma; Puva bath therapy; Scleroderma (overview); Scleroderma systemic; Sjögren's syndrome;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer