Pharmaceutical substances, dermatological, indicative concentrations

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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When prescribing external drugs (see below) , it is of primary importance to adhere to the recommended concentrations of the drug to be incorporated. The commission "Magistral Prescriptions" of the Deutsche Dermatologische Gesellschaft (German Dermatological Society) has listed therapeutic reference concentrations for the following listed medicinal products. The physician should indicate the exceeding of these concentrations by a special note. If such a note is missing, the pharmacy should evaluate the concentration as ambiguity and consult before preparation.

Literature
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  1. NRF (2003) 1.6. upper guide concentrations of dermatological drugs. DAC, New Prescription Form (NRF) 1.6. 12-13

Tables
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Active substance

Upper indicative concentration

betamethasone 17-valerate

0,15%

Capsaicin (also known as capsaicinoids in the form of cayenne pepper extract)

0,05%

Clioquinol

3,0%

Clobetasol propionate

0,05%

dexamethasone or dexamethasone acetate

0,05%

Dithranol (first prescription at the start of therapy)

0,1%

Dithranol (further regulation)

3%

Estradiol or estradiobenzoate

0,015%

Estriol

0,1%

Fuchsin on large areas of damaged skin

0,1%

Fuchsin small for brushing

0,5%

Gentamicin sulphate*

0,2%

Hydroquinone

3,0%

Hydrocortisone

1,0%

Potassium permanganate (ready-to-use solution)

0,001%

Methoxsalen(Ammoidin)

0,15%

Methylrosanilinium chloride (= gentian violet) on large areas of damaged skin

0,1%

Methylrosanilinium chloride small area for brushing

0,5%

Metronidazole

3,0%

Podophylline

15,0%

Salicylic acid (large area)

3,0%

Salicylic acid (small areas in ointments or patches)

60%

Coal tar(Pix lithanthracis)

10,0

Coal tar solution(Liquor carbonis detergens)

20,0

Testosterone/testosterone propionate

2,0%

Tretinoin

0,1%

triamcinolone acetonide

0,1%

Triclosan

3,0%

* Gentamicin is a reserve antibiotic for systemic use and is not recommended for cutaneous use. Therefore, the NRF does not contain prescriptions for external preparations containing gentamicin.

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Last updated on: 29.10.2020