Norethisterone acetate
Definition
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Half-life
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7–9 h
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Indication
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Amenorrhoea, oral contraception ("minipill"), supplementation of an estrogen substitution in the menopause.
Dosage and method of use
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- Amenorrhoea: In combination with an estrogen 1-2 mg/day p.o. over 12-14 days/cycle.
- Climacteric: 1-2 mg/day from the 19th to 25th day of the cycle.
Interactions
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If barbiturates, carbamazepine, griseofulvin, phenytoin, proxibarbital and rifampicin are taken at the same time, the contraceptive protection of the "minipill" is impaired. The toxicity of Ciclosporin A is increased when it is taken.
Preparations
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Primolut, Norethisteron Jenapharm, Noristerat
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Prof. Dr. med. Peter Altmeyer