Phenytoin
Definition
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Carboxamide-type barbiturate.
Indication
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Focal seizures, neurogenic pain, epidermolysis bullosa dystrophica dominans.
Undesirable effects
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Often (10-20% of patients) maculopapular exanthema. Rarely Stevens-Johnson syndrome, Lyell syndrome, hirsutism, exfoliative dermatitis.
Preparations
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Epanutine, Phenhydane, Phenytoin AWD, Centropil