Measles pemphigoid B05.8

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Morbilli bullosi; vesicolous morbilli

Definition
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Very rare disease similar to Toxic Epidermal Necrolysis with blisters and vesicles that occur in measles at the same time as the exanthema or a short time later in lesional areas of the skin.

Therapy
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Due to the life-threatening nature of the clinical picture, immediate intensive medical care with fluid and electrolyte control, metalline foil, vacuum mattress etc. High-dose glucocorticoids such as prednisolone (e.g. Solu-Decortin H) 1-1.5 mg/kg bw/day. In case of superinfection, systemic broad-spectrum antibiotics, e.g. cephalosporins such as ceftriaxone (e.g. Rocephin) 1mal/day 2 g i.v.; as soon as possible antibiotic therapy after antibiogram

Progression/forecast
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The lethality rate is about 50%.

Literature
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  1. Duke T, Mgone CS (2003) Measles: not just another viral exanthem. Lancet 361: 763-773
  2. Schneider-Schaulies S, ter Meulen V (2003) Pathogenic aspects of measles virus infections. Arch Virol Suppl 15: 139-158

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

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Last updated on: 29.10.2020