Leucocytoclasia

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Fragmentation of leukocytes by karyorrhexis; this results in small-particle nuclear fragments (nuclear dust). Leucocytoclasia is a pioneering phenomenon of leukocytoclastic vasculitis, but also occurs in other, etiologically completely different diseases, such as acute febrile neutrophilic dermatosis of dermatitis herpetiformis and anulare granuloma. Leucocytoclasia is also found in lymphocytic infiltrates, e.g. in lupus erythematosus profundus and in pseudolymphomas.

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Last updated on: 29.10.2020