Exanthema, acneiformes R21.x
Synonym(s)
acne medicamentosa
Definition
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Predominantly drug-induced skin symptoms with acne-like efflorescences, but without comedones. S.a. Acne medicamentosa.
Etiopathogenesis
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Possible triggers are above all: glucocorticoids ( steroid acne), also ACTH, diphenylhydantoin, quinine, isoniazid. Furthermore: halogen-containing drugs like iodine compounds, bromine compounds. Furthermore: lithium, phenobarbiturates, disulfiram, thyrostatic drugs (thiourea, thiouracil). Furthermore: vitaminB1, B6, B12, tyrosine kinase inhibitors like cetuximab (belongs together with gifitinib and erlotinib to a group of cancer therapeutics whose common feature is the blockade of the epidermal growth factor receptor[ EGF-receptor]; acne-like skin changes occur in > 80% of cases, about 2-6 weeks after the start of therapy).
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Localization
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Especially in the seborrhoeic zones and the upper arms.
Therapy
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Stop the medication. S.a.u. Acne medicamentosa.
Literature
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- Braun-Falco M et al (2006) Follicular drug reaction to cetuximab. dermatologist 57: 701-704
Recommended articles
Incoming links (7)
Acne medicamentosa; Bromoderm; Drug exanthema, acneiform; EGF receptors; Erlotinib; Folliculitis superficial; Malassezia folliculitis;Outgoing links (10)
Acne medicamentosa; EGF receptors; Erlotinib; Glucocorticosteroids; Iodine; Isoniazid; Komedo; Quinine; Steroid acne; Tyrosine kinase inhibitors;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
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Prof. Dr. med. Peter Altmeyer
