Dicrocoeliasis B66.2

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Synonym(s)

Lancet fluke infection; small liver flu

Definition
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Trematode infection by Dicrocoelium dendriticum.

Pathogen
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Dicrocoelium dendriticum (small liver fluke, lancet fluke); the adult worms are 5-12 x 1.4-2 mm in size, leaf-shaped, reddish, with a tree-like ("dendriticum") branched uterus and 2 suction cups of equal size. The eggs are 40 x 26 µm in size, dark brown, relatively thick-shelled, capped and contain mirazidia.

Occurrence/Epidemiology
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Rare human parasitosis (only about 100 cases have been described in the literature so far). Worldwide occurrence; Dicrocoelicum hospes, a closely related species, has been found in West and Central Africa.

Etiopathogenesis
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land snails take up the eggs; then, cercaria mature in the snails, which are released from the mucus bales; the maturing process lasts 3-5 months. The bales of slime are taken up by ants (e.g. by green fodder), which is absorbed by the final host. More frequent passagere egg excretion after consumption of liver containing Dicrocoelium worms.

Clinical features
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  • Integument: Icterus.
  • Essential systemic health disorders only in mass infestation: flatulence, loss of appetite, colicky pain in the upper abdomen, enlargement of the liver, anemia.

Diagnosis
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  • Detection of eggs in stool or duodenal juice (no consumption of liver during diagnosis)
  • Eosinophilia
  • No specific immunodiagnostics available, but serum antibodies against other trematode antigens.

Therapy
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Praziquantel: Single dose of 50 mg/kg bw p.o.

Prophylaxis
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No consumption of unwashed salad and other green plants.

Literature
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  1. Haswell-Elkins MR, Levri E (2003) Food-borne Trematodes. In: Cook GC, Zumla A Manson's Tropical diseases. WB Saunders, 21st Edition, pp. 1648-1716
  2. Ziegler K, Burchard GD, Meier-Brook A (1996) Liver and lung fluke infections. In: Knobloch J, tropical and travel medicine. Gustav Fischer

Incoming links (1)

Worm infections skin signs;

Outgoing links (2)

Icterus; Praziquantel;

Disclaimer

Please ask your physician for a reliable diagnosis. This website is only meant as a reference.

Authors

Last updated on: 29.10.2020