Cyproheptadine
Definition
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Serotonin and H1 antagonist.
Half-life
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6–9 h
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Indication
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Allergic reactions, pruritus, increased appetite.
Limited indication
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Pregnancy, MAO-A inhibitor.
Dosage and method of use
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- Adults/teenagers > 14 years: 3-4 times/day 4-8 mg p.o.
- Children 7-14 years: 2-3 times/day 4 mg p.o.
- Children 2-6 years: 2-3 times/day 2 mg p.o.
Undesirable effects
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Fatigue, serotoninergic syndrome, paresthesias, narrow-angle glaucoma.
Interactions
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Triyclic antidepressants can cause glaucoma or urinary retention, fluoxetine is reduced in its effect.
Contraindication
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Children < 2 years, acute asthma attack, mechanical ileus, gastric outlet stenosis.
Preparations
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Peritol
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Prof. Dr. med. Peter Altmeyer