Cyproheptadine

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Definition
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Serotonin and H1 antagonist.

Half-life
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6–9 h

Indication
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Allergic reactions, pruritus, increased appetite.

Limited indication
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Pregnancy, MAO-A inhibitor.

Dosage and method of use
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  • Adults/teenagers > 14 years: 3-4 times/day 4-8 mg p.o.
  • Children 7-14 years: 2-3 times/day 4 mg p.o.
  • Children 2-6 years: 2-3 times/day 2 mg p.o.

Undesirable effects
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Fatigue, serotoninergic syndrome, paresthesias, narrow-angle glaucoma.

Interactions
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Triyclic antidepressants can cause glaucoma or urinary retention, fluoxetine is reduced in its effect.

Contraindication
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Children < 2 years, acute asthma attack, mechanical ileus, gastric outlet stenosis.

Preparations
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Peritol

Outgoing links (2)

Antihistamines; Pruritus;

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Last updated on: 29.10.2020