HistoryThis section has been translated automatically.
Happle, 1990
DefinitionThis section has been translated automatically.
Systematized epidermal nevus with strongly hyperkeratotic skin lesions and histologically pronounced acantholysis. So far very rarely described clinical picture.
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Clinical featuresThis section has been translated automatically.
Strip-shaped plaque following the Blaschko lines, consisting of filiform, brown to brown-black hyperkeratoses, Cornua cutanea and hyperkeratoses reminiscent of giant comedones. During manual removal, pink, non-bleeding depressions remain in the skin.
HistologyThis section has been translated automatically.
Acanthosis and pronounced orthohyperkeratosis. Acantholytic cleft formation both suprabasal and in the upper epidermal layers.
Differential diagnosisThis section has been translated automatically.
Pemphigus chronicus benignus familiaris, dyskeratosis follicularis, recurrent linear acantholytic dermatosis of the vakilzadeh type, acantholytic dyskeratotic epidermal nevus, familial dyskeratotic comedones.
TherapyThis section has been translated automatically.
Excision if necessary.
LiteratureThis section has been translated automatically.
- Happle R et al (1990) Naevus corniculatus: a new acantholytic disorder. Br J Dermatol 122: 107-112
- Schulz-Kiesow M et al (1996) Hystrix-like keratosis with nail and joint-involvement: a new genodermatosis? Dermatology 192: 321-324
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Outgoing links (10)
Acantholysis; Acanthosis; Blaschko lines; Cornu cutaneum; Dyskeratosis follicularis; Epidermal nevus (overview); Giant comedo; Hyperkeratoses; Orthohyperkeratosis; Pemphigus chronicus benignus familiaris;Disclaimer
Please ask your physician for a reliable diagnosis. This website is only meant as a reference.
Prof. Dr. med. Peter Altmeyer