Collagen, injectable

Author: Prof. Dr. med. Peter Altmeyer

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Last updated on: 29.10.2020

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Injection of bovine collagen.

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Fine and deeper wrinkles and folds, as well as scars, especially in the facial area:
  • Isolated or multiple, soft, sunken scars, e.g. acne scars, after trauma, surgery, viral skin infections.
  • Cutaneous atrophy, e.g. after depot glucocorticoid injections.
  • Wrinkles and furrows due to the aging process of the skin, e.g. glabella, nasolabial folds.
The success of the treatment usually lasts between four and twelve months.

Notice! Due to a potential sensitization to collagen products or lidocaine, the treating physician must always carry out a skin test before the treatment. In case of unclear reactions, a second test should follow before the actual augmentation is performed.

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Overall, complications rarely occur. These include allergic reactions, formation of granulomatous infiltrates, temporary swelling and hardening of the tissue (possible even months after application; often after sun exposure, alcohol consumption).

Dosage and method of use
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Initially, tolerance is tested: injection of 0.1 ml collagen suspension intradermally on the inside of the forearm, observation of the test reaction over 4 weeks. If it is negative, therapeutic application strictly intracutaneously into the deep corium. Any initial overcorrection will disappear. How long the correction lasts varies from individual to individual, but usually the treatment must be repeated after several months.

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Autoimmune diseases such as rheumatoid arthritis, lupus erythematosus or dermatomyositis.

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Acne conglobata;


Last updated on: 29.10.2020