Synonym(s)
ICAM-1
DefinitionThis section has been translated automatically.
Acronym for"cluster of differentiation 54).
CD54 marked: endothelial cells, resting and activated lymphocytes and monocytes
Structure: Transmembrane glycoprotein (90 kDa)
Application: FACS, IHC (P) (G), IF
General informationThis section has been translated automatically.
Also known as Inter-Cellular-Adhesion-Molecule-1 (ICAM-1) CD54 is a ligand for CD11a (LFA-1). CD54 mediates the adhesion of T cells to antigen-presenting cells (APCs) and from T cell to T cell and T cell to B cell interactions. CD54 is also a receptor for rhinoviruses.
LiteratureThis section has been translated automatically.
- Hantschke M et al (2016) Immunohistological techniques. In: L. Cerroni et al. histopathology of the skin. Springer publishing house Berlin-Heidelberg p. 26-33.
Prof. Dr. med. Peter Altmeyer